Indogulf BioAg is a Manufacturer & Global Exporter of Fungcide for plants, bacillus subtilis, Lactobacillus Plantarum, Pseudomonas SPP & other Bacterias. Contact us @ +1 437 774 3831 < Microbial Species Biofungicides Biofungicides are effective biological agents that specifically control various fungal diseases in plants, significantly reducing the incidence of infections and promoting healthier, more resilient agricultural crops. Product Enquiry What Why How FAQ What it is Biofungicides are natural or biological agents used to control fungal diseases in crops. These agents can include beneficial fungi, bacteria, viruses, and other microorganisms that suppress fungal pathogens. Biofungicides offer an environmentally friendly alternative to synthetic fungicides, reducing chemical inputs and promoting sustainable agricultural practices. Why is it important Environmental Safety : Biofungicides are typically less harmful to non-target organisms and have minimal impact on beneficial insects, pollinators, and natural predators. Resistance Management : Biofungicides can help manage resistance issues that arise with synthetic fungicides, as they employ multiple modes of action against fungal pathogens. Residue Management : Biofungicides often leave little to no residues on crops, addressing concerns related to pesticide residues in food and the environment. How it works Biofungicides control fungal diseases through various mechanisms: Antagonism : Beneficial microorganisms compete with pathogenic fungi for nutrients and space, inhibiting their growth and colonization on plant surfaces. Parasitism : Some biofungicides parasitize fungal pathogens by penetrating their cells or producing enzymes that degrade fungal cell walls. Induced Resistance : Biofungicides can trigger systemic acquired resistance (SAR) in plants, enhancing their natural defense mechanisms against fungal infections. Antibiosis : Biofungicides produce secondary metabolites or antibiotics that directly inhibit fungal growth and spore germination. Biofungicides are often integrated into holistic disease management strategies, such as integrated pest management (IPM) programs, where they complement cultural practices and crop rotation to enhance efficacy. FAQ Content coming soon! Biofungicides Our Products Explore our range of premium Biofungicides tailored to meet your agricultural needs, providing effective and environmentally friendly protection against fungal diseases. Ampelomyces quisqualis Ampelomyces quisqualis is a mycoparasitic fungus widely known for its ability to parasitize powdery mildew fungi, making it an important biological control agent in agriculture. It infects and disrupts the reproductive structures of powdery mildew pathogens, reducing their spread and impact on crops. This fungus thrives on a variety of host plants, providing eco-friendly and sustainable solutions for managing powdery mildew in fruits, vegetables, and ornamental plants. Its natural mode of action minimizes the need for chemical fungicides, supporting integrated pest management strategies and promoting environmental health. View Species Bacillus subtilis Bacillus subtilis is a Gram-positive, endospore-forming bacterium widely studied for its roles in agriculture, biotechnology, and molecular biology. It functions as a biocontrol agent by producing antimicrobial compounds, enhances plant growth via phytohormone production and nutrient solubilization, and participates in bioremediation by degrading organic pollutants. Its utility in industrial processes stems from its production of enzymes, antibiotics, and biopolymers. As a model organism, B. subtilis provides insights into sporulation, biofilm formation, and gene regulation, underscoring its scientific and practical significance. View Species Bacillus tequilensis Bacillus tequilensis is a Gram-positive, endospore-forming bacterium with significant roles in agriculture and biotechnology. It enhances plant growth via phytohormone synthesis, nutrient solubilization, and antimicrobial activity against pathogens. Additionally, it contributes to bioremediation by degrading organic pollutants and produces industrially relevant enzymes. Its resilience to environmental stress underscores its potential for applications in sustainable agriculture, bioprocessing, and environmental remediation. View Species Chaetomium cupreum Chaetomium cupreum is a filamentous ascomycete fungus known for its biocontrol and biodegradation capabilities. It suppresses plant pathogens like Fusarium through antifungal metabolites and contributes to organic matter recycling via lignocellulose degradation. Its production of hydrolytic enzymes highlights its potential in sustainable agriculture and industrial biotechnology. View Species Fusarium proliferatum Non-pathogenic strains of Fusarium proliferatum offer promising potential in agriculture and biotechnology. These strains contribute to nutrient cycling by decomposing organic matter, enhancing soil health and fertility. Additionally, they are explored for their ability to produce industrially valuable enzymes and secondary metabolites that can be harnessed for biotransformation processes. Their metabolic diversity makes non-pathogenic F. proliferatum strains valuable for sustainable practices in agriculture and innovative applications in biotechnology. View Species Lactobacillus plantarum Lactobacillus plantarum is a facultative heterofermentative bacterium with diverse applications in health, agriculture, food technology, and biotechnology. Known for its probiotic properties, it enhances gut health by modulating the microbiome, strengthening the intestinal barrier, and producing antimicrobial compounds that inhibit pathogens. In food systems, it drives fermentation processes, producing lactic acid and bioactive metabolites that preserve food and enhance nutritional value, including B vitamins and antioxidants. In agriculture, L. plantarum offers significant benefits by controlling bacterial plant diseases, enhancing seed germination and seedling growth, improving root development, and inducing plant defense mechanisms. It supports plant growth by improving nutrient availability, enriching soil microbiota, and suppressing phytopathogens through the production of organic acids and antimicrobial peptides. Its genetic adaptability and metabolic versatility also make it valuable for enzyme production, metabolic engineering, and bioremediation, highlighting its role in sustainable health, agriculture, and bioprocessing applications. View Species Pediococcus pentosaceus Pediococcus pentosaceus is a Gram-positive lactic acid bacterium widely recognized for its dual role as a probiotic and as a biofungicide in agriculture. It produces lactic acid and a suite of antimicrobial peptides known as pediocins, which inhibit a broad spectrum of plant pathogens. Beyond pathogen suppression, it promotes plant growth through nutrient solubilization and induction of systemic resistance. View Species Pseudomonas spp. Pseudomonas spp. are versatile Gram-negative bacteria widely recognized for their role in biological control and plant health management. These bacteria produce antimicrobial compounds, enzymes, and secondary metabolites that effectively suppress plant pathogens, including fungi and bacteria, reducing disease incidence in crops. In agriculture, Pseudomonas spp. serve as eco-friendly alternatives to chemical pesticides, supporting sustainable farming practices. They also enhance plant stress tolerance by improving nutrient availability, promoting root growth, and inducing systemic resistance in plants. Their multifaceted benefits make Pseudomonas spp. essential for integrated pest management and environmentally responsible agriculture. View Species Trichoderma harzianum Trichoderma harzianum is a beneficial fungus widely used in agriculture for its biocontrol properties and plant growth-promoting effects. It manages fungal pathogens and soil-dwelling nematodes by producing antifungal metabolites and parasitizing harmful fungi, protecting crops from diseases. In addition to disease management, T. harzianum enhances seed germination, promotes robust plant growth, and strengthens plant defense mechanisms. Its ability to improve soil health and plant resilience makes it a vital tool in sustainable agriculture and integrated pest management strategies. View Species Trichoderma spp. Trichoderma spp. are widely recognized for their biocontrol capabilities in managing plant pathogens and soil-dwelling nematodes. These fungi displace causative agents by competing for resources and space, effectively reducing colonization opportunities for harmful fungi. Additionally, Trichoderma spp. produce enzymes and antimicrobial compounds that suppress the growth of plant pathogenic fungi, making them essential for sustainable agriculture and integrated pest management. View Species Trichoderma viride Trichoderma viride is a beneficial fungus widely used in agriculture for its ability to manage fungal pathogens and soil-dwelling nematodes. It enhances the stress tolerance of plant hosts and provides protection against fungal diseases by producing antifungal compounds and promoting plant defense mechanisms. Its role in improving plant resilience and controlling soil-borne pathogens makes it a key tool in sustainable agriculture and integrated pest management practices. View Species 1 1 ... 1 ... 1 Resources Read all

Protect your crops from bacterial diseases, fungal infections and pests that pose a risk on your crop using our range of organic inputs Plant Protect Naturally Protect Your Plants from Diseases Safeguard your crops naturally with our Plant Protection solutions, offering effective pest and disease management while minimizing environmental impact and preserving beneficial ecosystem balance. Contact us What Why How What it is Our Plant Protect range consists of organic inputs formulated specifically to defend crops against bacterial diseases, fungal infections, and pests. These products are crafted from natural ingredients and biological agents that offer effective protection while maintaining environmental sustainability. Why is it important Protecting crops from bacterial diseases, fungal infections, and pests is critical for agricultural success. These threats can cause significant damage, leading to reduced yields, lower crop quality, and economic losses for farmers. Organic inputs provide a safe and sustainable alternative to chemical pesticides and fungicides, preserving soil health, biodiversity, and the overall ecosystem. By utilizing organic solutions, farmers can uphold food safety standards and meet consumer demand for environmentally friendly produce. How it works Our Plant Protect products harness the power of natural compounds and beneficial organisms. Organic fungicides combat fungal infections by inhibiting fungal growth and spore production, thereby preventing disease spread. Biopesticides target pests through various mechanisms such as disrupting their feeding habits, interfering with their reproductive cycles, or acting as repellents. These methods effectively manage pest populations while minimizing adverse effects on beneficial insects, wildlife, and human health. By integrating our Plant Protect solutions into their crop management practices, farmers can enhance crop resilience, reduce dependency on synthetic chemicals, and promote sustainable agricultural systems. This approach not only safeguards crops but also supports long-term soil fertility and ecosystem health, ensuring a healthier and more productive farming environment. Plant Protect Our Products Explore our natural solutions for safeguarding plants against diseases and pests, ensuring healthy and thriving crops. Trichoderma viride An organic-certified biopesticide that controls termites, locusts, root grubs, and soil-dwelling pests. Its fungal spores infect and kill a range of insects, making it a powerful tool for integrated pest management in sustainable farming. View Product Beauveria bassiana A broad-spectrum biological insecticide formulated as a wettable powder, Beauveria bassiana targets both larvae and adult stages of insect pests using entomopathogenic fungal spores, offering effective and eco-friendly pest control. View Product Bloom Up Reflective anti-transpirant from vegetable oil that enhances drought tolerance, reduces water loss, and improves crop health. Non-toxic and biodegradable. View Product Flyban A biological larvicide derived from naturally-occurring soil bacteria, Bacillus thuringiensis var Israelensis, effectively controlling larvae populations. View Product Insecta Repel Insecta Repel uses Bti toxins to target larvae of mosquitoes, fungus gnats, and blackflies, offering effective control with minimal environmental impact. View Product Larvicare Activates plant defense pathways against biotic stress, protecting biomolecules and cellular structures from various stressors. View Product Mealycare A biological insecticide containing Lecanicillium lecanii, controlling mealy bugs and sucking insects like thrips, aphids, and mites. View Product Metarhzium Anisopliae This biological fungicide combats seed and soil-borne diseases caused by fungi like Rhizoctonia and Fusarium. Ideal for seed dressing and soil application, it promotes healthier crop establishment and disease resistance.An organic-certified biopesticide that controls termites, locusts, root grubs, and soil-dwelling pests. Its fungal spores infect and kill a range of insects, making it a powerful tool for integrated pest management in sustainable farming. View Product Mitimax Provides extended control of mites by penetrating leaf tissue, reducing biotic stress, and protecting beneficial insects. View Product Neem Oil Natural pesticide from Neem seeds (Azadirachta indica) that targets pests while being safe for birds, mammals, and beneficial insects. View Product Pacify Organic, non-lethal rat repellent designed to drive rats from fields, safe for earthworms, grazing animals, and aquatic life. View Product Proteger A 5-in-1 organic formulation controlling biotic stress caused by pests, fungi, bacteria, and supplements Vitamin K to plants. View Product Th-Derma Bio fungicide with Trichoderma Harzianum (2 x 10⁶ CFU/g) that controls damping-off and root rot. Free from contamination, with 12-month shelf life. View Product Thripcare Protects crops from biotic stress caused by thrips and leaf miners by boosting plant defense mechanisms with antioxidants. View Product Troopmax A bacterial larvicide with high specificity, targeting pests while minimizing environmental impact and harm to non-target organisms. View Product 1 1 ... 1 ... 1 Resources Read all

Leading manufacturer and exporter of Nano Potassium Phosphate fertilizers. Boost your crops' growth with our advanced nano-tech solutions. < Nano Fertilizers Nano Potassium Phosphate Enters encapsulated, preventing antagonisms. Its organic P and K content replace ten times the inorganic supplements, ensuring optimal crop yield. It replaces dicalcium phosphate and phytase in animal feeds. Product Enquiry Download Brochure Benefits Builds Critical Nutrient Levels Supports the development of essential nutrients in plants. Enhances Plant Health Improves overall plant health and vigor. Helpful in Malabsorption Conditions Assists plants in efficiently absorbing nutrients. Increases Nutrient Holding Capacity Enhances the soil's ability to retain nutrients. Components Composition (%) w/w Phosphorous as P 4.6 Phosphorous as P2O5 11.5 Chloride 0.01 Max. Iron 0.0005% max. Arsenic 0.0005% max. Composition Dosage & Application Why choose this product Key Benefits Sustainability Advantage Additional Info FAQ Additional Info Compatibility: Compatible with chemical fertilizers and chemical pesticides Shelf life: Best before 24 months when stored at room temperature Packaging: 5 Ltx2/Corrugated Cardboard Box Symptoms of Potassium Phosphate Deficiency: Yellowing or browning of leaf margins Weak stems Poor fruit development Increased susceptibility to drought stress Why choose this product? Content coming soon! Key Benefits at a Glance Content coming soon! Sustainability Advantage Content coming soon! Dosage & Application Seed Soaking: Dilute with water at a ratio of 1:120 for vegetable seeds.Seed Dressing: Dilute with 10L of water for 100kg of field seeds.Root Dipping: Dilute with water at a ratio of 1:100–200.Drip Irrigation: Apply 750ml per acre once every 15 days.Foliar Application:Vegetative Phase: Apply 1.5L per acre once every 21 days.Reproductive Phase: Apply 1L per acre once every 15 days. FAQ Content coming soon! Related Products Hydromax Anpeekay NPK Nano Boron Nano Calcium Nano Chitosan Nano Copper Nano Iron Nano Potassium More Products Resources Read all

Probiotics are live microorganisms, primarily bacteria and yeast, that confer health benefits when consumed in adequate amounts. They are found in various foods and supplements and are known for their positive effects on the gut microbiome. < Microbial Species Probiotics We provide diverse bacterial and yeast probiotic strains sourced from natural habitats. Available in individual forms or ready-to-fill blends, our probiotics range from 5 billion to 200 billion CFU/g, supporting gut health for humans and animals. Product Enquiry What Why How FAQ What it is Probiotics are live microorganisms, primarily beneficial bacteria and yeast, that provide health benefits when consumed in adequate amounts. They are often referred to as "good" or "friendly" bacteria due to their role in maintaining a balanced gut microbiome. Probiotics can be found in a variety of foods, such as yogurt, kefir, sauerkraut, and kimchi, as well as in dietary supplements. These microorganisms work by colonizing the intestines, competing with harmful bacteria, and producing substances that inhibit the growth of pathogens. There are many different strains of probiotics, each with unique properties and benefits. Common strains include Lactobacillus and Bifidobacterium , which are known for their effectiveness in promoting digestive health and enhancing immune function. Why is it important Gut Health : Probiotics help maintain a balanced gut microbiome, which is crucial for proper digestion and nutrient absorption. Immune Support : They enhance immune function by promoting the growth of beneficial gut bacteria and inhibiting harmful pathogens. Animal Health : In animals, probiotics improve digestion, enhance nutrient absorption, and can reduce the incidence of gastrointestinal disorders. Mental Well-being : Emerging research suggests a connection between gut health and mental health, indicating probiotics may help alleviate symptoms of anxiety and depression. How it works Colonization : Probiotics adhere to the intestinal lining, where they multiply and establish a healthy microbial environment. Competition : By occupying space and resources, probiotics compete with harmful bacteria, reducing their ability to thrive and cause disease. Metabolite Production : Probiotics produce beneficial compounds, such as short-chain fatty acids (SCFAs), which nourish gut cells and promote a healthy gut barrier. Immune Modulation : Probiotics stimulate the production of immune cells and antibodies, enhancing the body's defense mechanisms against infections. FAQ Content coming soon! Probiotics Our Products Explore our premium Probiotics designed to enhance gut health and immunity for both humans and animals, promoting overall well-being and vitality through effective microbial balance. Bifidobacterium animalis Bifidobacterium animalis supports gut health, aids digestion, and boosts immunity, promoting a balanced intestinal flora for optimal digestive wellness. View Species Bifidobacterium bifidum Bifidobacterium bifidum supports digestive health and helps maintain a balanced gut microbiota for optimal digestion and nutrient absorption. View Species Bifidobacterium breve Bifidobacterium breve aids in digestion, enhances immune function, and promotes gut health in infants and children, ensuring healthy growth and development. View Species Bifidobacterium infantis Bifidobacterium infantis plays a vital role in digestion and helps establish a healthy gut environment, especially in infants during early development. View Species Bifidobacterium longum Bifidobacterium longum supports gut health, aids digestion, and helps reduce inflammation in the intestines, contributing to overall wellness. View Species Clostridium butyricum Clostridium butyricum produces butyrate, which nourishes colon cells, enhances gut barrier function, and supports overall gut health and metabolism. View Species Lactobacillus acidophilus Lactobacillus acidophilus helps digest lactose, improves gut health, and boosts the immune system, supporting overall digestive wellness. View Species Lactobacillus bulgaricus Lactobacillus bulgaricus aids in lactose digestion, promotes gut health, and is commonly used in yogurt production for probiotic benefits. View Species Lactobacillus casei Lactobacillus casei supports digestive health, enhances immune function, and helps balance gut flora, contributing to a healthy digestive tract. View Species Lactobacillus fermentum Lactobacillus fermentum aids in digestion, supports immune health, and has antioxidant properties that benefit gut health and overall well-being. View Species Lactobacillus gasseri Lactobacillus gasseri promotes gut health, supports weight management, and aids in digestion, helping maintain a healthy weight for optimal overall wellness. View Species Lactobacillus helveticus Lactobacillus helveticus helps improve digestion, boosts immune health, and may reduce anxiety and stress through its calming effects. View Species Lactobacillus johnsonii Lactobacillus johnsonii enhances gut health, supports immune function, and helps maintain a balanced intestinal microbiota for optimal health. View Species Lactobacillus lactis Lactobacillus lactis promotes gut health, aids in digestion, and enhances immune responses, supporting overall gastrointestinal health. View Species Lactobacillus paracasei Lactobacillus paracasei supports immune function, aids digestion, and helps maintain a balanced gut microbiome for improved gut health. View Species Lactobacillus reuteri Lactobacillus reuteri promotes digestive health, supports immune function, and may reduce colic in infants, improving overall comfort. View Species Lactobacillus rhamnosus Lactobacillus rhamnosus supports gut health, enhances immune function, and helps prevent gastrointestinal infections for better digestive health. View Species Lactococcus lactis Lactococcus lactis aids in dairy fermentation, supports gut health, and enhances immune responses, contributing to a balanced gut flora. View Species 1 2 1 ... 1 2 ... 2 Resources Read all

< Crop Kits Neem Plus Neem Plus is a water-soluble neem and karanja-based bio-formulation targeting over 400 crop pests. Product Enquiry Download Brochure Biodegradable and Residue-Free The pesticide is environmentally safe, fully biodegradable, and leaves no harmful residues. Safe and Compatible Harmless to beneficial insects and compatible with other pesticides and fungicides in pH ranges from 5.5 to 6.5. Resistance Prevention The limonoid spectrum in Neem Plus hinders the development of resistance in pests. Multi-Action Insect Control Acts as a repellent, antiovipositor, and insect growth regulator, disrupting key stages of the pest life cycle. Benefits Content coming soon! Composition Dosage & Application Additional Info Dosage & Application For Bollworm, White fly: Use 2.5–5 ml of formulation Dilute in 500–1000 ml of water Waiting period: 5 days before harvest For Thrips, Stem Borer, Leaf folder, Brown Plant Hopper: Use 1.5–2.5 ml of formulation Dilute in 500 ml of water Waiting period: 5 days before harvest HOW TO USE? Neem Protect can be mixed with water and used in spray pumps. Normally oil and water don’t mix, however NEEM PLUS comes with a ready-to-use formulation which you can directly mix with water and start using on your plants. Spray the mixed solution on all the leaves, especially the undersides. When spraying for the first time, drench the soil around the roots as well as it is even good for your soil. Instructions to Open Open the bottle outdoors with care. Do not shake the bottle before opening. The bottle has a double seal system — an external black cap and a white inner plug with a nozzle in the centre. After opening the black outer cap, the inner plug has to be pierced in the middle using any pointed tool. The nozzle should give way, with a small hole, through which the liquid fertiliser can pour out. Additional Info Storage Requirements Store below 40°C in a cool, dry, well-ventilated place. Keep away from sunlight, children, and animals. Do not store in metallic containers. Keep tightly closed when not in use. Handling Precautions Use standard hygiene and safety practices for agricultural products. Related Products Aminomax SP Annomax BioProtek Biocupe Seed Protek Silicomax Dates Pro BloomX More Products Resources Read all

Lactobacillus gasseri promotes gut health, supports weight management, and aids in digestion, helping maintain a healthy weight for optimal overall wellness. < Microbial Species Lactobacillus gasseri Lactobacillus gasseri promotes gut health, supports weight management, and aids in digestion, helping maintain a healthy weight for optimal overall wellness. Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram Product Enquiry Download Brochure Benefits Immune System Boost This strain enhances immune response by stimulating the production of immune cells and improving the body’s defense against infections. Digestive Health Enhancement It promotes digestive health by alleviating symptoms of diarrhea and constipation while maintaining overall gut function. Weight Management Support This probiotic may aid in weight management by reducing body fat and regulating appetite through gut microbiota balance. Support for Vaginal Health It helps maintain vaginal microbiota balance, potentially reducing the risk of infections and promoting overall reproductive health. Dosage & Application Additional Info Scientific References Mode of Action FAQ Scientific References Content coming soon! Mode of Action Content coming soon! Additional Info Key Features All microbial strains are characterized using 16S rDNA. All products are non-GMO. No animal-derived materials are used. The typical shelf life is 2 years. All strains are screened in-house using high-throughput screening methods. We can customize manufacturing based on the required strength and dosage. High-resilience strains Stable under a wide pH range Stable under a broad temperature range Stable in the presence of bile salts and acids Do not show antibiotic resistance Packaging Material The product is packaged in a multi-layer, ultra-high barrier foil that is heat-sealed and placed inside a cardboard shipper or plastic drum. Shipping Shipping is available worldwide. Probiotic packages are typically transported in insulated Styrofoam shippers with dry ice to avoid exposure to extreme high temperatures during transit. Support Documentation Certificate of Analysis (COA) Specifications Material Safety Data Sheets (MSDS) Stability studies (18 months) Certifications ISO 9001 ISO 22000 HACCP Halal and Kosher Certification (for Lactobacillus strains) FSSAI Dosage & Application Contact us for more details FAQ Content coming soon! Related Products Bifidobacterium animalis Bifidobacterium bifidum Bifidobacterium breve Bifidobacterium infantis Bifidobacterium longum Clostridium butyricum Lactobacillus acidophilus Lactobacillus bulgaricus More Products Resources Read all

Bacillus thuringiensis israelensis (Bti) is a naturally occurring bacterium that has revolutionized pest control with its environmentally friendly and highly effective approach. Bti specifically targets the larvae of mosquitoes, blackflies, and fungus gnats, making it an essential tool for managing pests in residential, agricultural, and commercial settings. When applied to breeding sites, Bti releases protein toxins that are ingested by the larvae. These toxins disrupt the larvae's digestive system, leading to their death within hours. Remarkably, Bti’s mechanism of action is species-specific, ensuring that it poses no harm to beneficial insects, plants, animals, or humans. Additionally, it breaks down quickly in the environment, leaving no harmful residues behind. This powerful yet safe solution is a cornerstone in integrated pest management, trusted by professionals worldwide for its ability to protect public health and the environment. From controlling mosquitoes that spread diseases to managing agricultural pests, Bti provides a sustainable alternative to chemical insecticides. < Microbial Species Bacillus thuringiensis israelensis Bacillus thuringiensis israelensis (Bti) is a naturally occurring bacterium that has revolutionized pest control with its environmentally friendly and highly effective approach. Bti specifically targets… Show More Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram Product Enquiry Download Brochure Benefits Targeted Pest Control Specifically targets and controls mosquito larvae, reducing mosquito populations. Environmental Safety Non-toxic to humans and other non-target organisms, safe for aquatic ecosystems. Effective and Specific Highly effective against mosquito larvae with minimal impact on other organisms. Biodegradable Breaks down naturally in the environment, leaving no harmful residues. Dosage & Application Additional Info Scientific References Mode of Action FAQ Scientific References (Rudd et al., 2023) – Describes the complex protein compartmentalization in Bti’s parasporal body and its role in larval toxicity. (Stalinski et al., 2016) – Investigates Cry toxin-specific receptor responses and resistance development in Aedes aegypti . (Boisvert et al., 2007) – Reviews two decades of Bti use in Canada for mosquito control and its environmental safety. (Tan et al., 2012) – Field trial showing reduction in dengue cases following Bti treatment in Malaysia. (Gunasekaran et al., 2002) – Demonstrates long-lasting larvicidal activity of sustained-release Bti formulations in polluted habitats. (Becker et al., 2018) – Reports no resistance development in Aedes vexans after 36 years of Bti application. (Allgeier et al., 2018) – Evaluates biochemical responses in amphibians exposed to Bti, relevant for non-target safety assessments. (Nasser et al., 2021) – Describes the development of hydrogel-based Bti formulations for sustained larvicidal activity. (Tilquin et al., 2008) – Provides evidence of Bti persistence in natural mosquito habitats post-application. Mode of Action Mode of Action – Bacillus thuringiensis subsp. israelensis (Bti) Bacillus thuringiensis subsp. israelensis (Bti) is a spore-forming, Gram-positive bacterium that produces insecticidal proteins during sporulation. These proteins accumulate in a parasporal crystalline inclusion body and include four major protoxins: Cry4Aa, Cry4Ba, Cry11Aa , and Cyt1Aa . Together, they form a highly potent and synergistic toxin complex specifically targeting the larval stages of dipteran insects, including Aedes , Culex , and Anopheles mosquitoes, as well as blackflies and fungus gnats. 1. Ingestion and Activation When Bti spores and crystals are ingested by susceptible insect larvae, the alkaline pH (~10–11) of the insect midgut solubilizes the crystal proteins. This allows the protoxins to be processed into their active toxin forms by midgut proteases. 2. Binding to Midgut Epithelial Receptors The activated Cry toxins (Cry4Aa, Cry4Ba, and Cry11Aa) bind to specific glycoprotein receptors—such as aminopeptidases, alkaline phosphatases, and cadherin-like proteins—on the brush border membrane of midgut epithelial cells. This binding is receptor-specific, accounting for the narrow host range and high target specificity of Bti. 3. Pore Formation and Cell Lysis Upon binding, Cry toxins insert into the membrane and oligomerize to form transmembrane pores. These pores disrupt the osmotic balance of epithelial cells, causing cell swelling, lysis, and ultimately midgut epithelium rupture. This leads to leakage of gut contents into the hemocoel and septicemia. 4. Cyt1Aa Synergism Cyt1Aa functions through a complementary mechanism. It binds to membrane lipids in a receptor-independent manner, forming pores itself and acting as a synergist for Cry toxins. Cyt1Aa improves Cry toxin binding by serving as a surrogate receptor and prevents resistance development by targeting different membrane components. 5. Mortality and Environmental Decay The physiological effect is rapid—larvae typically stop feeding within hours and die within 24 to 48 hours. Spores released into the insect hemocoel germinate, contributing to systemic infection and accelerating mortality. Importantly, Bti toxins are biodegradable, and their specificity means they pose no significant risk to non-target organisms , including humans, mammals, fish, amphibians, and most beneficial insects. 6. Resistance Management The multi-toxin composition of Bti is a critical feature for resistance prevention. The presence of both Cry and Cyt toxins, each with distinct binding sites and modes of membrane disruption, makes the development of resistance in field populations exceedingly rare, even under prolonged use. Additional Info Bacillus thuringiensis israelensis (Bti) is a Gram-positive, spore-forming bacterium that has transformed pest management. Known for its precision and environmental safety, Bti specifically targets insect larvae, such as mosquitoes, black flies, and fungus gnats, while leaving non-target organisms unharmed. Its role in integrated pest management (IPM) has made it a cornerstone for sustainable and ecologically sensitive pest control. Explore our microbial solutions for sustainable pest management here . How Bacillus thuringiensis israelensis Works Bti produces insecticidal crystalline proteins (ICPs), including Cry4A, Cry4B, Cry11A, and Cyt1A, which are lethal to insect larvae. The mechanism includes: Ingestion: Larvae consume Bti spores and toxins. Activation: In the alkaline midgut environment of larvae, the toxins become active. Binding: The toxins bind to gut receptors, forming pores in the gut lining. Larval Death: The resulting gut cell destruction and septicemia cause death. This targeted mechanism ensures safety for pollinators, mammals, and aquatic organisms. Applications of Bacillus thuringiensis israelensis Mosquito Control: Effective in managing mosquito larvae in standing water, urban drainage, and sewage systems. Targets mosquito species such as: Aedes spp. (dengue, Zika, chikungunya vectors) Anopheles spp. (malaria carriers) Culex spp. (West Nile virus vectors) Black Fly Management: Applied in rivers and streams to control black fly larvae, reducing diseases like river blindness and livestock infections. Agricultural and Greenhouse Pest Control Targets pests such as: Fungus gnats (Bradysia spp.) that harm plant roots. Non-biting midges and aquatic dipterans that disrupt ecosystems. Offers a safer alternative to chemical pesticides, protecting crops and beneficial insects. Environmental Applications Used in bioremediation efforts, reducing pest populations in contaminated water bodies and restoring ecological balance. Advantages of Bacillus thuringiensis israelensis Environmentally Friendly: Specifically targets pests without harming non-target species, preserving biodiversity. Resistance Management: Can be combined with other biological agents like Bacillus sphaericus to minimize resistance development. Cost-Effective Production: Advanced fermentation methods, including the use of sewage sludge as a substrate, make Bti production sustainable and affordable. Versatility: Effective in various settings, from mosquito control in urban areas to pest management in agriculture and greenhouses. How to Use Bacillus thuringiensis israelensis Mosquito Breeding Sites: Apply granules or liquids directly to standing water. Frequency: Reapply every 7–14 days during peak breeding seasons. Agricultural Use: Use as a foliar spray or soil drench for greenhouse crops. Black Fly Control: Apply in fast-flowing rivers and streams to target larvae. Dosage & Application Soluble Liquid: 4100 ITU per milligram / 1 x 10⁸ CFU per gram Foliar Application Dose: 0.5 - 1 ml / square metre of water body 1 Acre dose: 2 – 4 L 1 Ha dose: 5 – 10 L Apply on water bodies. Use lower doses for cleaner water and higher doses for polluted water bodies. Apply at 1-2 week intervals. Foliar Application Method Mix Bacillus Thuringiensis – Israelensis at recommended doses in sufficient water and spray on the water body. Apply at intervals of 1-2 weeks. Other Uses : It can be used for seed care. Mix 10g Bacillus subtilis with 10g crude sugar in sufficient water to make a slurry. Coat 1kg of seeds, dry in shade, and sow / broadcast / dibble in the field. Do not store treated / coated seeds for more than 24 hours. Note: Do not store Bacillus Thuringiensis – Israelensis solution for more than 24 hours after mixing with water. FAQ Is Bacillus thuringiensis israelensis safe for use near humans and pets? Yes, Bti is non-toxi c to humans, pets, and beneficial organisms like bees and fish. How does Bti compare to chemical pesticides? Unlike broad-spectrum chemical pesticides, Bti specifically targets larvae, minimizing collateral damage to the environment. Can Bti be used in organic farming? Absolutely. Bti is certified for organic use and aligns with sustainable agricultural practices. What pests does Bti target? It is highly effective against mosquito larvae, black flies, fungus gnats, and aquatic dipterans. Future Directions Enhanced Bioremediation: Genetic engineering could further optimize Bti for improved pollutant degradation and pest control. Industrial Scaling: Scaling Bti production for broader applications in mosquito control and agriculture. Integrated Pest Management Innovations: Expanding Bti’s role in sustainable pest control strategies for diverse ecosystems. Bacillus thuringiensis israelensis is a powerful tool for sustainable pest management. With its precision targeting, environmental safety, and versatility, Bti offers an eco-friendly alternative to chemical pesticides. Whether combating vector-borne diseases, managing agricultural pests, or restoring ecosystems, Bti is an indispensable part of integrated pest management programs. Learn more about how Bacillus thuringiensis israelensis can transform your pest control strategy. Contact us today. Related Products Bacillus popilliae Bacillus thuringiensis subsp. kurstaki Lysinibacillus sphaericus More Products Resources Read all

Bacillus firmus enhances phosphorus availability in soil, stimulates root growth, improves fruit quality, and protects against soil-borne diseases. Compatible with bio-pesticides and bio-fertilizers. < Microbial Species Bacillus firmus Bacillus firmus enhances phosphorus availability in soil, stimulates root growth, improves fruit quality, and protects against soil-borne diseases. Compatible with bio-pesticides and bio-fertilizers. Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram Product Enquiry Download Brochure Benefits Enhance Fruit Development and Quality Improves the size, taste, and overall quality of fruits. Increase Sugar Content in Fruits Elevates the sugar levels in fruits, leading to sweeter and more nutritious produce. Protection Against Drought and Diseases Provides resilience against drought conditions and some soil-borne diseases, ensuring healthier plant development. Promote Root Growth Stimulates the development of a robust root system, enhancing nutrient uptake and plant stability. Dosage & Application Additional Info Scientific References Mode of Action FAQ Scientific References 1. Nematode Biocontrol and Root Interaction Bacillus firmus I-1582 effectively degrades nematode eggs, colonizes plant roots, and induces systemic resistance in tomato via salicylic acid (SA) and jasmonic acid (JA) signaling pathways. Ghahremani et al., 2020 – Frontiers in Plant Science Culture filtrates of B. firmus induce paralysis and mortality in nematodes, inhibit egg hatching, and demonstrate antagonistic activity through secondary metabolites. Mendoza et al., 2008 – Biocontrol Science and Technology A split-root study demonstrated both localized and systemic effects of B. firmus GB-126 in suppressing soybean cyst and root-knot nematodes. Schrimsher et al., 2012 – Experimental Study 2. Plant Growth Promotion and Genomic Insights Whole-genome sequencing of strain TNAU1 revealed genes associated with indole-3-acetic acid (IAA) biosynthesis, nutrient solubilization (phosphorus and potassium), nitrate transport, nematicidal proteases, and antibiotic biosynthetic clusters. Settu et al., 2023 – Physiological and Molecular Plant Pathology 3. Enzyme Production and Biotechnological Applications An extracellular nuclease from B. firmus VKPACU-1 displays high specificity for RNA and DNA substrates, indicating potential for biocatalytic and bioremediation applications. Kumar & Kannan, 2011 – Nucleosides, Nucleotides & Nucleic Acids Two xylanases purified from B. firmus exhibit activity over a wide pH range and efficiently degrade xylan to xylo-oligosaccharides, supporting their use in biomass conversion. Tseng et al., 2002 – Enzyme and Microbial Technology 4. Immunomodulatory Properties B. firmus functions as a potent polyclonal B cell activator, enhancing the production of immunoglobulins (notably IgA and IgG) in vitro, with implications for probiotic and adjuvant applications. Prokešová et al., 2008 – Folia Microbiologica Mucosal administration of B. firmus significantly enhanced systemic and mucosal antibody responses to a model antigen in animal models, indicating its potential as a mucosal immunoadjuvant. Mlčková et al., 2001 – Immunology Letters Mode of Action 1. Nematode Control B. firmus produces bioactive secondary metabolites that paralyze and kill nematodes such as Meloidogyne incognita and Radopholus similis . Culture filtrates alone can reduce egg hatching and cause up to 96% mortality in nematode juveniles (Mendoza et al., 2008) , (Settu et al., 2023) . It also degrades nematode eggs directly and colonizes plant roots, creating a physical and chemical barrier against nematode infection (Ghahremani et al., 2020) . 2 . Induction of Plant Resistance In plants like tomato, B. firmus activates systemic resistance by upregulating salicylic acid (SA) and jasmonic acid (JA) pathway genes, helping the plant fight off nematodes and potentially other pathogens (Ghahremani et al., 2020) . These effects can be systemic or localized, depending on the crop and context (Schrimsher et al., 2012) . 3. Plant Growth Promotion Genome analysis reveals genes responsible for: IAA (Indole-3-acetic acid) production (a plant hormone) Phosphorus and potassium solubilization Nitrate transport These contribute to enhanced nutrient uptake and overall plant growth (Settu et al., 2023) . 4. Enzymatic Activity B. firmus secretes nucleases and xylanases, which break down DNA, RNA, and complex polysaccharides—helping degrade organic matter and releasing nutrients in the soil (Kumar & Kannan, 2011) , (Tseng et al., 2002) . 5. Immunomodulatory Effects In animal models, B. firmus stimulates both systemic and mucosal immune responses by increasing the production of immunoglobulins (IgA, IgG) and cytokines (e.g., IFN-γ), making it a candidate as an oral adjuvant or probiotic (Prokešová et al., 2008), (Mlčková et al., 2001). Additional Info Recommended Crops: Cereals, Millets, Pulses, Oilseeds, Fibre Crops, Sugar Crops, Forage Crops, Plantation crops, Vegetables, Fruits, Spices, Flowers, Medicinal crops, Aromatic Crops, Orchards, and Ornamentals. Compatibility: Compatible with Bio Pesticides, Bio Fertilizers, and Plant growth hormones but not with chemical fertilizers and chemical pesticides. Shelf Life: Stable within 1 year from the date of manufacturing. Packing: We offer tailor-made packaging as per customers' requirements. Dosage & Application Seed Coating/Seed Treatment : 1 kg of seeds will be coated with a slurry mixture of 10 g of Bacillus firmus and 10 g of crude sugar in sufficient water. The coated seeds will then be dried in shade and sow or broadcast in the field. Seedling Treatment : Dip the seedlings into the mixture of 100 grams of Bacillus firmus and sufficient amount of water. Soil Treatment : Mix 3-5 kg per acre of Bacillus firmus with organic manure/organic fertilizers. Incorporate the mixture and spread into the field at the time of planting/sowing. Irrigation : Mix 3 kg per acre of Bacillus firmus in a sufficient amount of water and run into the drip lines. FAQ What is Bacillus firmus? Bacillus firmus is a beneficial, spore-forming bacterium widely used in agriculture for biological nematode control and plant growth promotion. It also has potential uses in immunology and biotechnology. How does B. firmus control nematodes? It produces bioactive compounds that paralyze and kill nematodes such as Meloidogyne incognita and Radopholus similis. These compounds also reduce egg hatching and juvenile survival (Mendoza et al., 2008) . Can B. firmus boost plant immunity? Yes. It induces systemic resistance in plants like tomato by activating salicylic acid (SA) and jasmonic acid (JA) signaling pathways, helping plants defend against pests and diseases (Ghahremani et al., 2020) . How does it promote plant growth? B. firmus produces plant growth-promoting substances like indole-3-acetic acid (IAA) and helps solubilize nutrients like phosphorus and potassium, improving nutrient uptake and plant development (Settu et al., 2023) . What enzymes does B. firmus produce? It secretes nucleases that degrade DNA and RNA, and xylanases that break down plant cell walls. These enzymes assist in nutrient recycling and potential industrial applications (Kumar & Kannan, 2011) , (Tseng et al., 2002) . Does B. firmus have medical or probiotic uses? Yes. It stimulates the immune system, especially IgA and IgG production, and has shown adjuvant potential in mucosal immunization studies (Prokešová et al., 2008). 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Cellulomonas uda is a cellulolytic bacterium that plays a critical role in accelerating composting processes. By breaking down cellulose and other organic matter, it generates heat, which raises the compost temperature to levels that enhance the activity of other microorganisms. This synergistic action speeds up decomposition, improves nutrient cycling, and ensures the production of high-quality compost for agricultural and horticultural use. < Microbial Species Cellulomonas uda Cellulomonas uda is a cellulolytic bacterium that plays a critical role in accelerating composting processes. By breaking down cellulose and other organic matter, it generates… Show More Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram Product Enquiry Download Brochure Benefits Promotes plant growth and soil fertility By enhancing nutrient availability and soil structure, it supports healthier plant growth and improves overall soil fertility. Accelerates decomposition process Cellulomonas uda speeds up the breakdown of organic matter, enhancing composting efficiency. Eliminates presence of pathogens This bacterium contributes to creating a safer compost environment by reducing harmful pathogens. Reduces composting odor Cellulomonas uda helps to minimize unpleasant odors that can occur during the composting process. Dosage & Application Additional Info Scientific References Mode of Action FAQ Scientific References Content coming soon! Mode of Action Content coming soon! Additional Info Recommended Crops: Cereals, Millets, Pulses, Oilseeds, Fibre Crops, Sugar Crops, Forage Crops, Plantation crops, Vegetables, Fruits, Spices, Flowers, Medicinal crops, Aromatic Crops, Orchards, and Ornamentals. Compatibility: Compatible with Bio Pesticides, Bio Fertilizers, and Plant growth hormones but not with chemical fertilizers and chemical pesticides. Shelf Life: Stable within 1 year from the date of manufacturing. Packing: We offer tailor-made packaging as per customers' requirements. Dosage & Application Contact us for more details FAQ Content coming soon! Related Products Aspergillus niger Aspergillus oryzae Cellulomonas carate Cellulomonas gelida More Products Resources Read all

Thiobacillus denitrificans is a chemolithoautotrophic bacterium known for its role in the nitrogen and sulfur cycles. It oxidizes reduced sulfur compounds (e.g., sulfides, thiosulfates) and couples this process with denitrification, converting nitrates and nitrites into nitrogen gas. This bacterium thrives in diverse environments, including soils, aquatic systems, and wastewater, where it contributes to nutrient cycling and pollution mitigation. Its ability to remove nitrogen and sulfur compounds makes it valuable for bioremediation, wastewater treatment, and managing industrial effluents. T. denitrificans is integral to maintaining ecosystem health and supporting sustainable environmental management. < Microbial Species Thiobacillus denitrificans Thiobacillus denitrificans is a chemolithoautotrophic bacterium known for its role in the nitrogen and sulfur cycles. It oxidizes reduced sulfur compounds (e.g., sulfides, thiosulfates) and… Show More Strength 1 x 10⁹ CFU per gram / 1 x 10¹⁰ CFU per gram Product Enquiry Download Brochure Benefits Nutrient Cycling Contributes to the cycling of nutrients in soil and aquatic ecosystems, enhancing overall fertility and health. Nitrate Reduction Efficiently converts nitrates to nitrogen gas, playing a crucial role in the nitrogen cycle and soil health. Sulfide Oxidation Capable of oxidizing sulfides, aiding in the detoxification of environments contaminated with sulfur compounds. Acid Mine Drainage Mitigation Helps in treating acid mine drainage by neutralizing acidic environments, promoting ecosystem restoration. Dosage & Application Additional Info Scientific References Mode of Action FAQ Scientific References Content coming soon! Mode of Action Content coming soon! Additional Info Contact us for more details Dosage & Application Contact us for more details FAQ Content coming soon! Related Products Saccharomyces cerevisiae Bacillus polymyxa Thiobacillus novellus Thiobacillus thiooxidans Alcaligenes denitrificans Bacillus licheniformis Bacillus macerans Citrobacter braakii More Products Resources Read all